Federal Register: December 4, 2000 (Volume 65, Number 233)

DOCID: FR Doc 00-30712

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Public Health Service

NOTICE: NOTICES

ACTION: Meetings:

SUBJECT CATEGORY:

National Toxicology Program; National Toxicology Program (NTP) Board of Scientific Counselors Meeting; Review of Nominations for Listing in the 10th Report on Carcinogens: Revised Preliminary Agenda and Review Order

DOCUMENT SUMMARY:

This notice provides updated information and notes changes for the meeting of the NTP Board of Scientific Counselors' Report on Carcinogens (RoC) Subcommittee to be held on December 13, 14, & 15, 2000, at the Wyndham City Center, 1143 New Hampshire Ave., NW, Washington, DC 20037. On December 13, registration will begin at 9:00 am and the meeting will begin at 9:30 am. On December 14 & 15, the meeting will begin at 8:30 am. Preregistration is not required; however, persons requesting time to make oral, public comments are asked to notify Dr. Mary S. Wolfe, Executive Secretary, prior to the meeting (contact information given below).

Background

This meeting covers the peer review of nominations for listing in the 10th RoC, and includes opportunity for public input. An earlier notice of this meeting, which included information about the nominations, review order, solicitation of oral and written comments, and how to secure background documents for the nominations, was published in the Federal Register (October 17, 2000, Volume 65, Number 201, Pages 6135261354).

Changes in Review Order

While the agenda for this meeting remains preliminary, the order of the review as published in the previous notice has been altered as follows: the review of Chloramphenicol changes from six to five; Talc (Asbestiform and
[[Page 75727]]
NonAsbestiform) changes on the agenda from number seven to number six; and Estrogens, Steroidal changes from number five to number seven for review. Summary data and the revised, preliminary order for review of the nominations are listed in the table below:
Summary Data for Nominations to be Reviewed at the Meeting of the NTP Board of Scientific Counselors' Report on Carcinogens SubcommitteeDecember 13, 14, & 15, 2000 Tentative Nomination to be reviewed/cas number Primary uses or exposures To be reviewed for review order Broad Spectrum UV Radiation and UVA, Solar and artificial sources Listing in the 10th 1 UVB and UVC. of ultraviolet radiation. Report. Chloramphenicol/(56757).............. Used widely as an antibiotic Listing in the 10th 5 since the 1950s. Report. Estrogens, Sterodial................... Estrogens are widely used in Listing in the 10th 7 postmenopausal therapy and Report. in oral contraceptives for women.
Metallic Nickel & Nickel Alloys........ Widely used in commercial Listing in the 10th 4 applications for over 100 Report. years.
Methyleugenol/(93152)................ Flavoring agent used in Listing in the 10th 3 jellies, baked goods, Report. nonalcholoic beverages, chewing gum, candy, and ice cream. Also used as a fragrance for many perfumes, lotions, detergents and soaps. Talc/(14807966) (Asbestiform and (Non Asbestiform talc (i.e. talc Listing in the 10th 6 Asbestiform). containing Asbestiform Report. fibers) occurs in various geological settings around the world. Occupational exposure occurs during mining, milling and processing. Nonasbestiform talc (i.e. talc not containing asbestiform fibers) occurs in various geological settings around the world. Occupational exposure occurs during mining, milling and processing. Exposure to general population occurs through use of products such as cosmetics.
Trichloroethylene (TCE)/(79016)...... Trichloroethylene is widely Upgrade to Known......... 2 used as a solvent with 8090% used worldwide for degreasing metals.
Wood Dust.............................. It is estimated that at least Listing in the 10th 8 two million people are Report. routinely exposed occupationally to wood dust worldwide. Nonoccupational exposure also occurs. The highest exposures have generally been reported in wood furniture and cabinet manufacturer, especially during machine sanding and similar operations.

The RoC Subcommittee will provide separate recommendations for each of the agents, substances, mixtures or exposure circumstance listed in the table above. This includes separate recommendations for Broad Spectrum UV Radiation and for UVA, for UVB, and for UVC; for Metallic Nickel and for Nickel Alloys, and for Talc Asbestiform and for Talc NonAsbestiform.

The agenda and a roster of Subcommittee members is available on the NTP web homepage at http://ntpserver.niehs.nih.gov/ and upon request from Dr. Wolfe (Dr. Mary S. Wolfe, P.O. Box 12233, A307, Research Triangle Park, NC 27709 (telephone 919/5413971; FAX 919/5410295; email wolfe@niehs.nih.gov). Summary minutes for the previous meeting are available on the NTP web homepage and upon request from Dr. Wolfe.

Dated: November 21, 2000.
Samuel H. Wilson,
Deputy Director, National Institute of Environmental Health Services. [FR Doc. 0030712 Filed 12100; 8:45 am] BILLING CODE 414001M

SUMMARY:

National Toxicology Program—; Scientific Counselors Board,

DOCUMENT BODY 2:

This notice provides updated information and notes changes for the meeting of the NTP Board of Scientific Counselors' Report on Carcinogens (RoC) Subcommittee to be held on December 13, 14, & 15, 2000, at the Wyndham City Center, 1143 New Hampshire Ave., NW, Washington, DC 20037. On December 13, registration will begin at 9:00 am and the meeting will begin at 9:30 am. On December 14 & 15, the meeting will begin at 8:30 am. Preregistration is not required; however, persons requesting time to make oral, public comments are asked to notify Dr. Mary S. Wolfe, Executive Secretary, prior to the meeting (contact information given below).

Background

This meeting covers the peer review of nominations for listing in the 10th RoC, and includes opportunity for public input. An earlier notice of this meeting, which included information about the nominations, review order, solicitation of oral and written comments, and how to secure background documents for the nominations, was published in the Federal Register (October 17, 2000, Volume 65, Number 201, Pages 6135261354).

Changes in Review Order

While the agenda for this meeting remains preliminary, the order of the review as published in the previous notice has been altered as follows: the review of Chloramphenicol changes from six to five; Talc (Asbestiform and
[[Page 75727]]
NonAsbestiform) changes on the agenda from number seven to number six; and Estrogens, Steroidal changes from number five to number seven for review. Summary data and the revised, preliminary order for review of the nominations are listed in the table below:
Summary Data for Nominations to be Reviewed at the Meeting of the NTP Board of Scientific Counselors' Report on Carcinogens SubcommitteeDecember 13, 14, & 15, 2000 Tentative Nomination to be reviewed/cas number Primary uses or exposures To be reviewed for review order Broad Spectrum UV Radiation and UVA, Solar and artificial sources Listing in the 10th 1 UVB and UVC. of ultraviolet radiation. Report. Chloramphenicol/(56757).............. Used widely as an antibiotic Listing in the 10th 5 since the 1950s. Report. Estrogens, Sterodial................... Estrogens are widely used in Listing in the 10th 7 postmenopausal therapy and Report. in oral contraceptives for women.
Metallic Nickel & Nickel Alloys........ Widely used in commercial Listing in the 10th 4 applications for over 100 Report. years.
Methyleugenol/(93152)................ Flavoring agent used in Listing in the 10th 3 jellies, baked goods, Report. nonalcholoic beverages, chewing gum, candy, and ice cream. Also used as a fragrance for many perfumes, lotions, detergents and soaps. Talc/(14807966) (Asbestiform and (Non Asbestiform talc (i.e. talc Listing in the 10th 6 Asbestiform). containing Asbestiform Report. fibers) occurs in various geological settings around the world. Occupational exposure occurs during mining, milling and processing. Nonasbestiform talc (i.e. talc not containing asbestiform fibers) occurs in various geological settings around the world. Occupational exposure occurs during mining, milling and processing. Exposure to general population occurs through use of products such as cosmetics.
Trichloroethylene (TCE)/(79016)...... Trichloroethylene is widely Upgrade to Known......... 2 used as a solvent with 8090% used worldwide for degreasing metals.
Wood Dust.............................. It is estimated that at least Listing in the 10th 8 two million people are Report. routinely exposed occupationally to wood dust worldwide. Nonoccupational exposure also occurs. The highest exposures have generally been reported in wood furniture and cabinet manufacturer, especially during machine sanding and similar operations.

The RoC Subcommittee will provide separate recommendations for each of the agents, substances, mixtures or exposure circumstance listed in the table above. This includes separate recommendations for Broad Spectrum UV Radiation and for UVA, for UVB, and for UVC; for Metallic Nickel and for Nickel Alloys, and for Talc Asbestiform and for Talc NonAsbestiform.

The agenda and a roster of Subcommittee members is available on the NTP web homepage at http://ntpserver.niehs.nih.gov/ and upon request from Dr. Wolfe (Dr. Mary S. Wolfe, P.O. Box 12233, A307, Research Triangle Park, NC 27709 (telephone 919/5413971; FAX 919/5410295; email wolfe@niehs.nih.gov). Summary minutes for the previous meeting are available on the NTP web homepage and upon request from Dr. Wolfe.

Dated: November 21, 2000.
Samuel H. Wilson,
Deputy Director, National Institute of Environmental Health Services. [FR Doc. 0030712 Filed 12100; 8:45 am] BILLING CODE 414001M