Federal Register: August 14, 2006 (Volume 71, Number 156)
DOCID: FR Doc 06-6871
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
ACTION: Patent licenses; non-exclusive, exclusive, or partially exclusive:
DOCUMENT ACTION: Notice.
Prospective Grant of Exclusive License: Recombinant Antibodies and Immunoconjugates Targeted to CD-22 Bearing Cells and Tumors
DATES: Only written comments and/or applications for a license which are received by the NIH Office of Technology Transfer on or before October 13, 2006 will be considered.
This is notice, in accordance with 35 U.S.C. 209(c)(1) and 37 CFR Part 404.7(a)(1)(i), that the National Institutes of Health, Department of Health and Human Services, is contemplating the grant of an exclusive patent license to practice the inventions embodied in U.S. Patent Application No. 09/381,497, filed September 20, 1999, entitled ``Recombinant Antibodies and Immunoconjugates Targeted to CD22 Bearing Cells and Tumors'' [E0591997/0US07]; European Patent Application No. 98912977.0, filed October 13, 1999, entitled ``Recombinant Antibodies and Immunoconjugates Targeted to CD22 Bearing Cells and Tumors'' [E0591997/0EP05]; Japanese Patent Application No. 10 540812, filed March 19, 1998, entitled ``Recombinant Antibodies and Immunoconjugates Targeted to CD22 Bearing Cells and Tumors'' [E059 1997/0JP06]; Australian Patent No. 740904, issued on February 28, 2002, entitled ``Recombinant Antibodies and Immunoconjugates Targeted to CD22 Bearing Cells and Tumors'' [E0591997/0AU03]; and Canadian Patent Application No. 2284665, filed March 19, 1998, entitled ``Recombinant Antibodies and Immunoconjugates Targeted to CD22 Bearing Cells and Tumors'' [E0591997/0CA04]; to Cambridge Antibody Technology, Ltd., which has offices in Cambridge, United Kingdom. The patent rights in these inventions have been assigned to the United States of America.
The prospective exclusive license territory may be worldwide, and the field of use may be limited to the use of the BL22 and HA22 and variants thereof as claimed in the licensed patent rights for the treatment of hematologic malignancies.
Cambridge Antibody Technology, Ltd.,
This technology is a family of two (2) immunoconjugates, each consisting of an antiCD22 antibody coupled to a killing moiety, specifically pseudomonas exotoxin (PE38). The immunotoxins are both targeted towards CD22, and may be useful as therapeutic agents for the treatment of leukemias, lymphomas and autoimmune diseases. Further, BL22 has shown success in early clinical trials.
The prospective exclusive license will be royalty bearing and will comply with the terms and conditions of 35 U.S.C. 209 and 37 CFR 404.7. The prospective exclusive license may be granted unless within sixty (60) days from the date of this published notice, the NIH receives written evidence and argument that establishes that the grant of the license would not be consistent with the requirements of 35 U.S.C. 209 and 37 CFR 404.7.
Applications for a license in the field of use filed in response to
this notice will be treated as objections to the grant of the
contemplated exclusive license. Comments and objections submitted to
this notice will not be made available for public inspection and, to
the extent permitted by law, will not be released under the Freedom of Information Act, 5 U.S.C. 552.
Dated: July 28, 2006.
Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health.
[FR Doc. 066871 Filed 81106; 8:45 am]
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