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ENVIRONMENTAL PROTECTION AGENCY

Environmental Protection Agency

FRL ID: [FRL-8495-5; Docket ID No. EPA-HQ-ORD-2007-1083]

NOTICE: NOTICES

ACTION: Toxic and hazardous substances control:

DOCUMENT ACTION: Notice of Public Comment Period.

SUBJECT CATEGORY: Draft Toxicological Review of 1,2,3-Trichloropropane: In Support of the Summary Information in the Integrated Risk Information System (IRIS)

DATES: The public comment period begins November 16, 2007, and ends January 15, 2008. Technical comments should be in writing and must be received by EPA by January 15, 2008. EPA intends to submit comments from the public received by this date for consideration by the external peerreview panel.

DOCUMENT SUMMARY: EPA is announcing a public comment period for the external review draft document titled, ``Toxicological Review of 1,2,3 Trichloropropane: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (NCEAS1669). The EPA intends to consider comments and recommendations from the public and the expert panel meeting, which will be scheduled at a later date and announced in the Federal Register, when EPA finalizes the draft document. The public comment period will provide opportunities for all interested parties to comment on the document. EPA intends to forward public comments, submitted in accordance with this notice, to the external peerreview panel prior to the workshop for their consideration.

EPA is releasing this draft document solely for the purpose of pre dissemination public review under applicable information quality guidelines. This document has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency policy or determination.

The draft document is available via the Internet on NCEA's home page under the Recent Additions and the Data and Publications menus at http://www.epa.gov/ncea. When finalizing the draft document, EPA intends to consider any public comments that EPA receives in accordance with this notice.

SUMMARY: Integrated Risk Information System—; 1,2,3-trichloropropane; toxicological review in support of summary information,

SUPPLEMENTAL INFORMATION

I. Summary of Information About the Integrated Risk Information System (IRIS)

IRIS is a database that contains potential adverse human health effects information that may result from chronic (or lifetime) exposure to specific chemical substances found in the environment. The database (available on the Internet at http://www.epa.gov/iris) contains qualitative and quantitative health effects information for more than 500 chemical substances that may be used to support the first two steps (hazard identification and doseresponse evaluation) of a risk assessment process. When supported by available data, the database provides oral reference doses (RfDs) and inhalation reference concentrations (RfCs) for chronic health effects, and oral slope factors and inhalation unit risks for carcinogenic effects. Combined with specific exposure information, government and private entities can use IRIS data to help characterize public
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health risks of chemical substances in a sitespecific situation and thereby support risk management decisions designed to protect public health.
II. How To Submit Technical Comments to the Docket at
http://www.regulations.gov

Submit your comments, identified by Docket ID No. EPAHQORD2007 1083 by one of the following methods:

http://www.regulations.gov: Follow the online instructions for submitting comments.

Email: ORD.Docket@epa.gov.

Fax: 2025661753.

Mail: Office of Environmental Information (OEI) Docket (Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202 5661752.

Hand Delivery: The OEI Docket is located in the EPA Headquarters Docket Center, EPA West Building, Room 3334, 1301 Constitution Ave., NW., Washington, DC. The EPA Docket Center Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is 2025661744. Such deliveries are only accepted during the docket's normal hours of operation, and special arrangements should be made for deliveries of boxed information.

If you provide comments by email or hand delivery, please submit one unbound original with pages numbered consecutively, and three copies of the comments. For attachments, provide an index, number pages consecutively with the comments, and submit an unbound original and three copies.

Instructions: Direct your comments to Docket ID No. EPAHQORD 20071083. Please ensure that your comments are submitted within the specified comment period. Comments received after the closing date will be marked ``late,'' and may only be considered if time permits. It is EPA's policy to include all comments it receives in the public docket without change and to make the comments available online at http://www.regulations.gov, including any personal information provided, unless a comment includes information claimed to be confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Do not submit information that you consider to be CBI or otherwise protected through http://www.regulations.gov or email. The http://www.regulations.gov Web site is an ``anonymous access'' system, which means EPA will not know your identity or contact information unless you provide it in the body of your comment. If you send an e mail comment directly to EPA without going through http://www.regulations.gov, your email address will be automatically captured and included as part of the comment that is placed in the public docket and made available on the Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact information in the body of your comment and with any disk or CDROM you submit. If EPA cannot read your comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic files should avoid the use of special characters, any form of encryption, and be free of any defects or viruses. For additional information about EPA's public docket, visit the EPA Docket Center homepage at http://www.epa.gov/epahome/dockets.htm.

Docket: All documents in the docket are listed in the http://www.regulations.gov index. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center.

Dated: November 2, 2007.
Rebecca Clark,
Deputy Director, National Center for Environmental Assessment. [FR Doc. E722444 Filed 111507; 8:45 am]
BILLING CODE 656050P

FOR FURTHER INFORMATION CONTACT For information on the public comment period, contact the Office of Environmental Information Docket; telephone: 2025661752; facsimile: 2025661753; or email:
ORD.Docket@epa.gov.

If you have questions about the document, contact Martin Gehlhaus, IRIS Staff, National Center for Environmental Assessment, (8601D), U.S. EPA, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 2025641596; facsimile: 2025650075; gehlhaus.martin@epa.gov (e mail).