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FRL ID: [FRL-8496-9]

NOTICE: NOTICES

ACTION: Reports and guidance documents; availability, etc.:

DOCUMENT ACTION: Notice of extension of public comment period.

SUBJECT CATEGORY: Notice of Extension of Public Comment Period for the External Review Draft of a ``Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility From Early-Life Exposure to Carcinogens''

DOCUMENT SUMMARY: On September 27, 2007, the U.S. Environmental Protection Agency (EPA) released for public comment the External Review Draft of the ``Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility from EarlyLife Exposure to Carcinogens'' (or Framework). At that time, a 60day public comment period was announced. This notice announces a 30day extension of the public comment period; the public comment period will end 90 days from September 27, 2007, the date of the original Federal Register Notice (72 FR 54910). Visit http://www.epa.gov/fedrgstr/EPAGENERAL/2007/September/Day27/g19119.pdf ) for further information. Members of the
public may obtain the draft interim guidance from http://www.epa.gov/osa/mmoaframework; or consult the person listed under FOR FURTHER INFORMATION CONTACT.

SUMMARY: Framework for determining a mutagenic mode of action for carcinogenicity; ... assessing susceptiblity from early-life exposure to carcinogens,

FOR FURTHER INFORMATION CONTACT For more information, contact Resha Putzrath, Ph.D., Office of the Science Advisor, Mail Code 8105R, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone number: (202) 5643229; fax number: (202) 5642070, email: putzrath.resha@epa.gov.

Dated: November 8, 2007.
George M. Gray,
EPA Science Advisor.
[FR Doc. E722508 Filed 111507; 8:45 am]
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